Operating an Airbnb (i.e. Short-Term Rental, or STR) in San Diego requires several permits and adherence to specific regulations designed to ensure responsible hosting and community harmony. Following the outlined steps and maintaining compliance with local laws, you can convert your home into a short-term rental. Here are the necessary permits and regulations for renting a short-term rental (e.g. Airbnb, VRBO rental) in San Diego, California.